Tuesday, August 25, 2020

Yeo soft drinks division SBU strategic market plan Case Study

Yeo sodas division SBU vital market plan - Case Study Example Yeo Hiap Seng sodas division was picked as the key specialty unit in the promoting plan. It is a division of the organization in Singapore and it is the unit accused of the soda pops promoting in the organization. Being an enormous organization with various items, YHS (Yeo Hiap Seng) endeavors to enhance the presentation of the organization through the individual commitment of the subdivisions.Soft drinks give off an impression of being gradually yet consistently surpassing hot beverages as the biggest refreshment segment on the planet (Deloitte, 2008). A report by Zenith global shows that the utilization of the sodas is ascending by 5% every year. As an industry, soda pops advertise is quickly growing (Aqua-Trace, 2008). The business is looked by a few market patterns and factors that either push or pull them to lead them toward the path that we see them to proceed.The organizations working in this industry are along these lines commonly looked by a few difficulties that incorporate ever-changing customer tastes, in wrinkled accentuation on items wellbeing and the rising intensity of the retailers at the worldwide level.Due to the few factors that are thought of while having an image into what occurs with this industry, it is imperative to investigate the open doors for process improvement which could at last lead to better quality items and in the process ensure security of the item for the shopper while simultaneously enhancing assets to give best benefits. A perspective on all the significant business factors with an eye into the future gives an inspirational possibility that at last makes sure about an organization's business or activities later on. Albeit United States remains the greatest market as of now, Asia prone to be the significant driver of the deals sooner rather than later (Deloitte, 2008). The soda pops industry is envisioned by opening into the whole drink industry. The drink business has had its chances and difficulties. Consistent dynamism in buyer requests and inclinations, call for better approaches for drawing in new clients while keeping up the old ones. Since this is the best way to expand deals and thus accomplish development. The drink organizations endeavor to court clients, offer great items, effectively circulate them, guarantee wellbeing and keep costs low. These must all occur with the eyes despite everything open in order to ready to abuse new open doors by propelling new items. The organization in this way prevails by rapidly misusing new chances. As a subsection of the refreshment business; the soda pops showcase has been developing essentially, especially in the developing markets which incorporate Asia as a key player

Saturday, August 22, 2020

Media in China Term Paper Example | Topics and Well Written Essays - 3000 words

Media in China - Term Paper Example This is altogether off-base. The Chinese individuals have venerated the shading red since old occasions . . . The shading red speaks to life, essentialness, youth, zest, brilliance, striking quality, quality, totality of life power. (Bandurski, 2011, para. 14) In a question and answer session a week ago, Chongqing city hall leader Huang Qifan reported that CTV could hope to lose 300 million yuan in promoting incomes because of its â€Å"red† makeover. The city will apparently finance its nearby TV slots under CTV at a pace of 150 million yuan. Reason for the Study CTV’s progressive change comes when neoliberalism and the commercialization of media are the predominant and overpowering stages on which China is making its rising on the worldwide economy. While the gathering state has kept up its firm hold, and is step by step modernizing its techniques for control, advertise powers have penetrated and changed each part of the media framework. Gathering state power is progr essively merging with the intensity of capital in the Chinese media through a progression of interlaced procedures of convenience, assignment, state-built market combination, and particular joining of private and outside media capital (Zhao, 2004, p. 1). This combination of gathering state and market power has brought about a media framework that safeguards the prosperity of the country’s political and practical world class, while hushing and underestimating any restriction (Zhao, 2004). Subsequently, columnists abstain from uncovering clashing stories to keep up social equalization. The issue of media and transparency must be comprehended as far as first class and well known legislative issues and reconstituted class and force relations. It has gotten standardized to stay away from inclusion of residential... CTV’s progressive change comes when neoliberalism and the commercialization of media are the predominant and overpowering stages on which China is making its climb on the worldwide economy.  While the gathering state has kept up its firm grasp and is progressively modernizing its strategies for control, advertise powers have saturated and changed each part of the media framework. Gathering state power is progressively meeting with the intensity of capital in the Chinese media through a progression of entwined procedures of convenience, appointment, state-designed market union, and particular joining of private and outside media capital (Zhao, 2004, p. 1). This combination of gathering state and market power has brought about a media framework that protects the prosperity of the country’s political and monetary tip top while quieting and underestimating any resistance (Zhao, 2004). Accordingly, columnists abstain from uncovering clashing stories to keep up social parit y. The issue of media and receptiveness must be comprehended as far as world class and well known legislative issues and reconstituted class and force relations. It has gotten systematized to dodge inclusion of household social clashes, and spotlight on diversion and stocks, for money related remunerating in a market is driven media framework. Because of a personal stake in the solidness of Chinese media, significant US media aggregates will ensure that venture through one-sided and emotional media inclusion to smother social dangers from lower classes. CTV’s progressive change comes when neoliberalism and the commercialization of media are the prevailing and overpowering stages on which China is making its climb on the worldwide economy.  While the gathering state has kept up its firm hold and is step by step modernizing its strategies for control, showcase powers have penetrated and changed each part of the media framework. Gathering state power is progressively meeting with the intensity of capital in the Chinese media through a progression of interlaced procedures of settlement, allocation, state-designed market union, and specific fuse of private and remote media capital (Zhao, 2004, p. 1). This combination of gathering state and market power has brought about a media framework that protects the prosperity of the country’s political and financial world class while quieting and minimizing any restriction (Zhao, 2004). Accordingly, writers abstain from uncovering clashing stories to keep up social equalization. The issue of media and receptiveness must be comprehended as far as tip top and well known governmental issues and reconstituted class and force relations. It has gotten organized to maintain a strategic distance from inclusion of household social clashes, and spotlight on diversion and stocks, for budgetary compensating in a market is driven media framework. Because of a personal stake in the steadiness of Chinese media, significan t US media aggregates will secure that venture through one-sided and emotional media inclusion to stifle social dangers from lower classes.â

Wednesday, August 5, 2020

How to Overcome Your Fear of Alcohol Withdrawal

How to Overcome Your Fear of Alcohol Withdrawal Addiction Alcohol Use Withdrawal and Relapse Print How to Overcome a Fear of Alcohol Withdrawal After Quitting By Buddy T facebook twitter Buddy T is an anonymous writer and founding member of the Online Al-Anon Outreach Committee with decades of experience writing about alcoholism. Learn about our editorial policy Buddy T Medically reviewed by Medically reviewed by Steven Gans, MD on August 05, 2016 Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital. Learn about our Medical Review Board Steven Gans, MD Updated on December 13, 2019 becon / Getty Images More in Addiction Alcohol Use Withdrawal and Relapse Binge Drinking Children of Alcoholics Drunk Driving Addictive Behaviors Drug Use Nicotine Use Coping and Recovery Have you ever wanted to quit drinking alcohol but were hesitant to do so because you feared that the withdrawal symptoms would be too severe? You are not alone. Many people are afraid the withdrawal symptoms  could be dangerous if they quit drinking. You may have tried to quit drinking alcohol before and discovered that the symptoms you experienced were more severe than you anticipated. Maybe you decided to go back to drinking just to relieve those symptoms. Alcohol withdrawal symptoms are the primary reason that many people quickly relapse when they attempt to quit. Uncomfortable Symptoms of Alcohol Withdrawal Can Be Reduced Make no mistake about it, alcohol withdrawal symptoms can be severe, and in some cases fatal.?? If you are a daily drinker, a heavy drinker or a frequent binge drinker, suddenly quitting will likely produce a wide range of uncomfortable symptoms. But today there is help available for people trying to give up alcohol, even after a lifetime of heavy drinking. There is treatment available that can greatly reduce or eliminate most of the symptoms of alcohol withdrawal. Alcohol Withdrawal Symptoms Seek Help Rather Than Quitting Cold Turkey Without Support The key to quitting alcohol while avoiding unpleasant withdrawal symptoms is asking for help. If you have decided that it is in your best interest to stop drinking, seek help from your family doctor or primary healthcare provider. There are specific medical treatments that your physician can provide you with that will stop or reduce most of the symptoms you would normally experience if you quit cold turkey. Benzodiazepines (tranquilizers) are the main treatment for symptoms of withdrawal, like the shakes, and are also key to preventing and treating delirium tremens (DTs). ?? You may be given beta-blockers to reduce your heart rate and anti-seizure medications in case you do go into the DTs.?? Your healthcare provider may also suggest vitamins and dietary changes help with your withdrawal symptoms.?? Treatment Options for Alcohol Withdrawal Symptoms Professional Detox Programs Another alternative, especially if you have experienced severe withdrawal in the past, is to check yourself into a professional detoxification facility. Detox programs involve short-term (usually less than seven days) inpatient treatment during which specially trained professionals monitor your withdrawal closely and administer medications as needed. One advantage of in-patient detox is that you will be away from your usual drinking triggers and therefore be less likely to pick up a drink to stop the symptoms when they begin.?? And no, you do not have to be falling-down drunk to check into detox. People voluntarily check in every day. Bottom Line If you need to quit drinking, dont let alcohol withdrawal scare you off. There are medications and treatments available today that can help you get through those first early days of no alcohol consumption. You dont have to do it on your own. Alcohol Withdrawal From Day 1 to Day 30

Saturday, May 23, 2020

The Fedex Stock s Price - 1126 Words

FedEx has produced superior financial returns to its shareholder in last couple of year. It has a worldwide business with a broad portfolio of transportation, e-commerce and business services. It consistently ranked among world’s most trusted and admired employers. The revenue has been consistently increasing and expected to reach at 45 billion in next year. EPS is also about 5.5 and the expected P/E ratio is 14.3 which show its growth potential. With the stock’s beta of 1.27 and latest dividend payout ratio of 9%, it can be expected that it will give a superior result in near future and thus it is one of the best alternatives for investment. The FedEx stock’s price range in last year was 101.95 – 155.31. Currently its stock’s price is†¦show more content†¦From 2005, FedEx has decided to eliminate the classified structure of Board and allowed for the annual election of all directors. Investors’ interest has been protected and tried to maintain the full integrity in business operation. It is tried to ensure the disclosure of all the material information and a complete transparency so all investors have access of clear factual information. The next year’s growth rate is expected to be 21.10% which is higher than the Industry and market growth. This higher growth rate is based on it’s a strong financial base, huge market capitalization, higher growth potential, consistent earnings record, diversified portfolio and a reputation it earned in past several years. The estimated beta of firm is about 1.27. This figure is retrieved from a reliable website-www.finance.yahoo.com. To calculate the firm’s required rate of return, CAPM model is applied as follows: One year US Treasury rate of return = 0.10% One year Market return on SP 500 = 24.40% The beta of FedEx stock = 1.27 Hence, the firm’s required rate of return = 0.10 + 1.27*(24.40 – 0.10) = 30.96% For year ended 31st Mar’14, Cash flow from operating activities is $4,264 million and Cash flow from investing activities is $3,551 million. Hence, Free cash flow (FCF) to the firm will be Cash flow from Operating activities less Cash flow from Investing activities, i.e. $4,264 - The Fedex Stock s Price - 1126 Words FedEx has produced superior financial returns to its shareholder in last couple of year. It has a worldwide business with a broad portfolio of transportation, e-commerce and business services. It consistently ranked among world’s most trusted and admired employers. The revenue has been consistently increasing and expected to reach at 45 billion in next year. EPS is also about 5.5 and the expected P/E ratio is 14.3 which show its growth potential. With the stock’s beta of 1.27 and latest dividend payout ratio of 9%, it can be expected that it will give a superior result in near future and thus it is one of the best alternatives for investment. The FedEx stock’s price range in last year was 101.95 – 155.31. Currently its stock’s price is $152.68. The latest dividend was declared on Jun’17, 2014 and it was $0.20 per share. Its annual dividend yield is 0.40%. On Jun’9, 2014, The Board of Director of FedEx declared the quarterly cash dividend of $0.20 per share which was $0.5 higher than the previous quarter’s dividend. Dividend was payable on Jul’13, 2014. Corporate Governance is a set of rule and processes by which a company is directed and controlled. FedEx is committed to highest quality of corporate governance. It has independent board of directors having spirit of corporate governance reform. Compliance standards are met in accordance of Sarbanes-Oxley Act of 2002 and the New York Stock Exchange’s corporate governance listing standards. Code of Business conduct andShow MoreRelatedThe Fedex Stock s Price1126 Words   |  5 PagesFedEx has produced superior financial returns to its shareholder in last couple of year. It has a worldwide business with a broad portfolio of transportation, e-commerce and business services. It consistently ranked among world’s most trusted and admired employers. The revenue has been consistently increasing and expected to reach at 45 billion in next year. EPS is also about 5.5 and the expected P/E ratio is 14.3 which show its growth potential. With the stock’s beta of 1.27 and lates t dividendRead MoreThe Fedex Stock s Price1126 Words   |  5 PagesFedEx has produced superior financial returns to its shareholder in last couple of year. It has a worldwide business with a broad portfolio of transportation, e-commerce and business services. It consistently ranked among world’s most trusted and admired employers. The revenue has been consistently increasing and expected to reach at 45 billion in next year. EPS is also about 5.5 and the expected P/E ratio is 14.3 which show its growth potential. With the stock’s beta of 1.27 and latest dividendRead MoreQuestions On Fedex Financial Performance1048 Words   |  5 Pagesovercome by any of them. In FedEx case, their financials have been their weakest spot. FedEx poor financial performance has been a big problem for the company, proof of this is the downgrade FedEx bonds have had in past years. In UPS, I would say one of their inhibiting factors is their lack of innovation. UPS has not been able to innov ate and work with the technological improvements. Part of this is due of being first in the market, UPS was founded in 1907, FedEx in 1971, FedEx has gained a reputationRead MoreEssay about Fedex Corp. vs. United Parcel Service, Inc.1266 Words   |  6 PagesFedex Corp. vs. United Parcel Service, Inc. FedEx will produce superior financial returns for shareowners by providing high value-added supply chain, transportation, business, and related information services through focused operating companies competing collectively, and managed collaboratively, under the respected FedEx brand. —FedEx mission statement (excerpt) We serve the evolving distribution, logistics, and commerce needs of our customers worldwide, offering excellence and value inRead MoreBusiness Analysis : United Parcel Service1354 Words   |  6 Pages The company that I chose was United Parcel Service. UPS s main business is the time-definite delivery of packages and documents worldwide. Today, UPS is a global company with one of the most recognized brands in the world. They have become the world s largest package delivery company and a leading global provider of specialized transportation and logistics services. (Ups.com.,2014). Along with UPS this study examines the financial management policies of another competitor in the Air Delivery Read MoreFedex And Ups . Fedex Also Known As Federal Express Is712 Words   |  3 PagesFedex and UPS Fedex also known as Federal Express is an organization that offers transportation, web based business and business administrations with the assistance of a few organizations that are working together under one brand. The organization has four business portions, for example, FedEx Express, FedEx Ground, FedEx Freight, and FedEx Services (FedEx Corporation, 2012). Mean while United Postal Services (UPS) is the world s greatest package movement association and pioneer in giving overallRead MoreA Global Brand Of The Fedex Corporation ( Fedex )1469 Words   |  6 Pageshave all successfully gone global. FedEx Corporation (FedEx), incorporated on October 2, 1997, provides a portfolio of transportation, e-commerce and business services under the FedEx brand. The company offers its services through companies constituting four business segments: FedEx Express, FedEx Ground, FedEx Freight and FedEx Services. FedEx Express offers a range of domestic and international shipping services for delivery of packages and freight. FedEx Ground provides business and residentialRead MoreUps Key Success Factors900 Words   |  4 Pagesfaster than the world market growth. How is FedEx performing? How, if at all, do its performance and plans affect your assessment of the sustainability of UPSs current performance? Federal Express is performing moderately well. The sale have grown by 7.65% compared to the industry 5.49%, However the net profit margin is 5.67% compared to the industry figure of 7.70%. The return on Assets is 8.52% whereas the industry figure is 11.10%. Two of FedEx strategies that have worked are its tie up withRead MoreUps Key Success Factors912 Words   |  4 Pagesfaster than the world market growth. How is FedEx performing? How, if at all, do its performance and plans affect your assessment of the sustainability of UPSs current performance? Federal Express is performing moderately well. The sale have grown by 7.65% compared to the industry 5.49%, However the net profit margin is 5.67% compared to the industry figure of 7.70%. The return on Assets is 8.52% whereas the industry figure is 11.10%. Two of FedEx strategies that have worked are its tie up withRead MoreLiquidity Ratios Are Defined As A Class Of Financial Metrics900 Words   |  4 Pagesare defined as a class of financial metrics that is used to determine a company s ability to pay off its short-terms debts obligations. Generally, the higher the value of the ratio, the larger the margin of safety that the company possesses to cover short-term debt (Liquidity Ratios, 2006). In simple terms this states for every dollar of current debt FedEx has, they have $1.96 to pay it off. Pertaining to FedEx, each of the ratios have significantly increased from the previous year. This may

Monday, May 11, 2020

The Theory Of Psychoanalysis On The Unconscious Phases Of...

The theory of Psychoanalysis In the early 1800s, Psychologist and researchers were fervent in postulating and hypothesizing. Searching earnestly for answers to the many questions that were prevalent in those days. The theory of Psychoanalysis was one of such theory that was founded. Psychoanalysis emphases on the unconscious phases of personality development. The main tenets of this theory are characterized into four subsections. Firstly, it states that early childhood experiences are important in life’s later development. Secondly, it declares that psychosexual stages are linked to major developmental needs and challenges. Thirdly, the theory of Psychoanalysis emphases put forth that, each phase can include conflicts. That how people†¦show more content†¦At an early time when the medical community did not believe in the use of psychological means in the treatment of mental illness, he showed that some cases of mental illness were psychological in origin and therefore could be treated by psycholo gical means like psychoanalysis. The most important period of the Freud s life is related to his self-analysis, discoveries from this period influenced his entire psychoanalytic work. This experimental Psychologist impacted medical science a great deal, (a community to which he belonged) especially in the area of Psychiatry and mental illness diagnosis and treatment. One of my favorite quote by Sir Sigmund Freud is, â€Å"Being entirely honest with oneself is a good exercise.† Sigmund Freud was Born in Přà ­bor, Czech Republic, in May of 1856 and later died on September 23, 1939, in Hampstead, United Kingdom, at the age of 83 years. The main tenets of the psychoanalysis theory are characterized into four subsections. Firstly, it states that early childhood experiences are important in life’s later development. Secondly, it declares that psychosexual stages are linked to major developmental needs and challenges. Thirdly, the theory of Psychoanalysis emphases put forth that, each phase can include conflicts. That how people experience and resolve conflicts determine their personality patterns later in life. Other psychologist worked to help move the ball forward with regards to the theory ofShow MoreRelated A Look Into Psychoanalysis Essay1469 Words   |  6 Pages nbsp;nbsp;nbsp;nbsp;nbsp;Psychoanalysis had its beginning with the discovery that a person in complete physical health could experience an illness with physical symptoms that stemmed from things trapped in the subconscious known as hysteria. Charcot, a French neurologist tried to liberate the mind through hypnosis. A Viennese physician, Josef Breuer, carried this purging further with a process based on his patient, Anna O., revealing her thoughts and feelings to him. Sigmund Freud took Breuer’sRead MoreFreud s Theory Of Psychology1683 Words   |  7 Pagespsychoanalytic theory. According to The American Heritage, â€Å" Psychoanalysis is the theory of personality developed by Freud that focuses on repression and unconscious forces and includes the concepts of infantile sexuality, resistance, transference, and division of the psyche into the id, ego, and superego† (Houghton Mifflin, 2005). This theory has had such a big impact on psychology, that it is even practiced to day. Many other theories, have been developed from the basis of the psychoanalysis theory. TheRead MoreSigmund Freud: A Very Brief Biography1582 Words   |  7 Pages INTRO Sigmund Freud is considered one of the most influential figures in modern psychology. He is best known as the father of psychoanalysis. He developed several important theories of personality, including the theories of mind, the id, the ego, and the superego, life and death instincts, psychosexual development, and defense mechanisms. He also published many books that helped shape psychology into what it is today. EARLY LIFE Sigismund Schlomo Freud was born in Moravia, Czech RepublicRead More The Influence of Sigmund Freud on Society Essay822 Words   |  4 PagesSociety The late nineteenth century marked a number of radical developments on science, art, and philosophy. Although the lives of humans used to be constantly at the mercy of nature, during this time, humans began harnessing its power and eventually started controlling it. A sudden urge to look beyond the surface of things became widespread. Sigmund Freud looked beyond the effects of behavior and explored the unconscious. He significantly changed the way the world viewed behavior by explainingRead MorePsychology : Psychology And Psychology1018 Words   |  5 Pagespsychological schools represent the major theories of psychology. The first stream of well-founded thought this was structuralism was defended by Wilhelm Wundt. Immediately other theories began to emerge and compete for dominance in psychology. In the past, psychologists often identified exclusively with one school of thought, through time this has changed. Today, most psychologists have an eclectic vision of psychology. Often they based only on ideas and theories from different schools rather than searchRead MoreSigmund Freud s Theory Of Psychosexual Development1550 Words   |  7 Pagesthe father of psychoanalysis. In his life Freud was a medical doctor, psychologist, physiologist, and an influential thinker. Freud is most known for his in depth exploration of the human mind. In this paper I take an in depth look at the life Freud lived, all the way from when he was born to when he tragically died. I also take a look at multiple influential theories he created which led to many different breakthrough when it comes to the study of the mind. His most popular theory that involvesRead MoreThe Surface Represents The Consciousness Essay1029 Words   |  5 Pagesconduct. The unconscious mind acts as a storage of primitive wishes and motivation kept under control and arbitrated by the preconscious area. Sigmund Freud emphasized the significance of the unconscious mind, and an essential presumption of Freudian hypothesis which is the unconscious mind represents conduct to a more prominent degree than people had suspected. Certainly, the objective of psychoanalysis is to make the unconscious conscious. His psychoanalytic theory of personality challenges thatRead MoreFREUD’S PSYCHODYNAMIC THEORY AND THE RECENT APPROACH Essay1738 Words   |  7 PagesThe psychodynamic theory has its own perspective, thus ranging us with numerous experimental findings and studies. According to Freud, the psychodynamic theory has developed from the psychosexual stages of an individual; in terms of normal development, at which, is a start at bi rth and throughout his adulthood. There are multiple factors structuring of human personality; and therefore, Freud had introduced us his theory in achieving it from the state of the unawareness. Ermann also focused on theRead MoreThe Human Person Is That It Needs Relationship For Its Existence1625 Words   |  7 Pagesconcept of the attachment theory. Bowlby was a psychoanalyst, so the paper also considers other significant individuals who have contributed to the psychoanalytic school in the history of psychology. Such individuals include Sigmund Freud, Anna Freud, Klein, Ainsworth, Main, and Winnicott. In his book: Attachment and Loss, Bowlby (1969) stated: â€Å"For long, psychoanalysts have been at one in recognizing a child’s first human relationship as the foundation stone of his personality; but there is as yet noRead MoreSigmund Freud s Psychoanalysis Theory2380 Words   |  10 Pages Contemporaries of Sigmund Freud’s Psychoanalysis Theory Kevin Stout Florida Institute of Technology Abstract Sigmund Freud created psychoanalysis, a system through which an expert unloads oblivious clashes in light of the free affiliations, dreams and dreams of the patient. Psychoanalytic hypothesis is a strategy for exploring and treating identity issue and is utilized as a part of psychotherapy. Included in this hypothesis is the way to go that things that happen

Wednesday, May 6, 2020

I’m Going! a Comedy in One Act Free Essays

I’m Going! A Comedy in One Act Keshalla Mabry ENG 125 : Introduction to Literature Andrea Moak February 25, 2013 Literature can be expressive. It can be expressed in many different ways. Some use writing, some use pictures and print, or even dramatic and musical works of art. We will write a custom essay sample on I’m Going! a Comedy in One Act or any similar topic only for you Order Now In this essay I will be using the Reader-Response Approach to analyze a piece of literature. I have chosen the short play I’m Going! A Comedy in One Act, by dramatist Tristan Bernard. I will include why the literary work captured my interest, how it made me feel, and how it has formed or change my connection with literature. Firstly, let me describe the approach I will be taking towards this piece of literature. The Reader-Response approach I can’t just rely on feelings and opinions, I must read and make connections and respond on those connections. With that being said I will start with what captured my interest. While going through the first couple of lines in the dialogue I began to paint a picture of Henri and Jeanne. Henri came across to me as a stubborn old scrooge who wants things his way or no way. He is very persistent about the races and his wife not attending. As they continue to converse he brings up all the reasons why she shouldn’t accompany him to the races. He complains about having to get a special carriage if she goes, and how he would have to buy her a ladies ticket. Basically, he is trying to think of anything possible to keep his wife at home. He would rather be alone at the races so he can â€Å"have a good time†, because according the dialogue he can only accomplish this goal if he goes alone. The wife on the other hand tries to reason with him and let him know that she is willing to have a good time and she would rather be out with him than to be home alone and neglected. I for one can sympathize with Jeanne. She is a woman who has a regular Sunday routine and it goes on unchanged. I too have a Sunday routine that is consistent. She would like to get out of the house for once and attend the races with her husband, who feels as if she present it will spoil his goodtime. My fiance is the same way. Every other Friday he and his friends go out to the bar. Sometimes the friends bring a date and other times they don’t. Well, one Friday I decided I wanted to go with. He (my fiance) kept making excuses for me not to go. He would say, â€Å"Oh love, the boys and I are just going to have some beers†. Or he would let me know ahead of time they were just going to hang out and watch ESPN. He made sure that I knew there was no room for me in his boys’ night out. So I can definitely feel Jeanne’s pain. A little farther in the conversation Henri tells Jeanne that he is off to the races, as he does she says that she will be alone and neglected. He insists that the weather was too bad for her to attend and that she should stay home. After some debate about changing clothes and some sulking from both parties Jeanne eventually decided that she will allow her husband to leave and amuse himself with the races because she wants to go visit with a friend of hers. Once Henri hears this and at first all he can think about is the fact that he can go to the races alone. Once he sees that Jeanne is content and easy going about him leaving he begins to have second thoughts about going. He sees that Jeanne is not acting mad or sad and he thinks that something must be fishy and he asks to see the telegram that she is sending to her friend. This seems to me as if Henri may have a trust issue with Jeanne. She shows him the telegram and he insists that this was a signal so that Jeanne could meet some other man. After reading this far, I came to the conclusion that Henri must have had some kind of infidelity and he was afraid that his wife was taking his decision to go to the races as an opportunity to get even so to speak. This is just insecurities and guilt catching up with him. He doesn’t want her at the races, he doesn’t want her visiting friends, he wants her at home alone and neglected. This way he knows where she is and can pop up on her at any time. Eventually Jeanne decided to stay at home while Henri attended the races. After reading this short play I began to wonder if this type of trickery goes on in other relationships. It seems to me that Henri has some trust issues, possibly from something he has done in the past and he is scared that it may catch up to him. But should the man or woman in the relationship be made to feel unhappy, sad, mad, alone, and neglected while the other party does as he or she pleases? Henri had no sympathy for his wife’s feelings or concerns. The only thing on his mind was him going to the races while she stayed at home alone and social deprived. Relationships take two people to give and take considerably and evenly, no one person should dictate the relationship or benefit more than the other. I have also run across other work of literature that shows the female as the subordinate to the husband or vice versa. I’m beginning to enjoy this course now more than ever, I can see the connections and feel where the characters and authors are coming from so to speak. With all the literary terms and works or literature that I’ve covered so far, they have me expressing my thoughts, feelings, and interpretations already and we are just scratching the surface. Bibliography Clugston, R. W. (2010). Journey into literature. San Diego, California: Bridgepoint Education, Inc Litlang Ltda. (2007). Types of literary criticism. Retrieved from http://www. textetc. com/criticism. html How to cite I’m Going! a Comedy in One Act, Papers I’m Going! a Comedy in One Act Free Essays I’m Going! A Comedy in One Act Keshalla Mabry ENG 125 : Introduction to Literature Andrea Moak February 25, 2013 Literature can be expressive. It can be expressed in many different ways. Some use writing, some use pictures and print, or even dramatic and musical works of art. We will write a custom essay sample on I’m Going! a Comedy in One Act or any similar topic only for you Order Now In this essay I will be using the Reader-Response Approach to analyze a piece of literature. I have chosen the short play I’m Going! A Comedy in One Act, by dramatist Tristan Bernard. I will include why the literary work captured my interest, how it made me feel, and how it has formed or change my connection with literature. Firstly, let me describe the approach I will be taking towards this piece of literature. The Reader-Response approach I can’t just rely on feelings and opinions, I must read and make connections and respond on those connections. With that being said I will start with what captured my interest. While going through the first couple of lines in the dialogue I began to paint a picture of Henri and Jeanne. Henri came across to me as a stubborn old scrooge who wants things his way or no way. He is very persistent about the races and his wife not attending. As they continue to converse he brings up all the reasons why she shouldn’t accompany him to the races. He complains about having to get a special carriage if she goes, and how he would have to buy her a ladies ticket. Basically, he is trying to think of anything possible to keep his wife at home. He would rather be alone at the races so he can â€Å"have a good time†, because according the dialogue he can only accomplish this goal if he goes alone. The wife on the other hand tries to reason with him and let him know that she is willing to have a good time and she would rather be out with him than to be home alone and neglected. I for one can sympathize with Jeanne. She is a woman who has a regular Sunday routine and it goes on unchanged. I too have a Sunday routine that is consistent. She would like to get out of the house for once and attend the races with her husband, who feels as if she present it will spoil his goodtime. My fiance is the same way. Every other Friday he and his friends go out to the bar. Sometimes the friends bring a date and other times they don’t. Well, one Friday I decided I wanted to go with. He (my fiance) kept making excuses for me not to go. He would say, â€Å"Oh love, the boys and I are just going to have some beers†. Or he would let me know ahead of time they were just going to hang out and watch ESPN. He made sure that I knew there was no room for me in his boys’ night out. So I can definitely feel Jeanne’s pain. A little farther in the conversation Henri tells Jeanne that he is off to the races, as he does she says that she will be alone and neglected. He insists that the weather was too bad for her to attend and that she should stay home. After some debate about changing clothes and some sulking from both parties Jeanne eventually decided that she will allow her husband to leave and amuse himself with the races because she wants to go visit with a friend of hers. Once Henri hears this and at first all he can think about is the fact that he can go to the races alone. Once he sees that Jeanne is content and easy going about him leaving he begins to have second thoughts about going. He sees that Jeanne is not acting mad or sad and he thinks that something must be fishy and he asks to see the telegram that she is sending to her friend. This seems to me as if Henri may have a trust issue with Jeanne. She shows him the telegram and he insists that this was a signal so that Jeanne could meet some other man. After reading this far, I came to the conclusion that Henri must have had some kind of infidelity and he was afraid that his wife was taking his decision to go to the races as an opportunity to get even so to speak. This is just insecurities and guilt catching up with him. He doesn’t want her at the races, he doesn’t want her visiting friends, he wants her at home alone and neglected. This way he knows where she is and can pop up on her at any time. Eventually Jeanne decided to stay at home while Henri attended the races. After reading this short play I began to wonder if this type of trickery goes on in other relationships. It seems to me that Henri has some trust issues, possibly from something he has done in the past and he is scared that it may catch up to him. But should the man or woman in the relationship be made to feel unhappy, sad, mad, alone, and neglected while the other party does as he or she pleases? Henri had no sympathy for his wife’s feelings or concerns. The only thing on his mind was him going to the races while she stayed at home alone and social deprived. Relationships take two people to give and take considerably and evenly, no one person should dictate the relationship or benefit more than the other. I have also run across other work of literature that shows the female as the subordinate to the husband or vice versa. I’m beginning to enjoy this course now more than ever, I can see the connections and feel where the characters and authors are coming from so to speak. With all the literary terms and works or literature that I’ve covered so far, they have me expressing my thoughts, feelings, and interpretations already and we are just scratching the surface. Bibliography Clugston, R. W. (2010). Journey into literature. San Diego, California: Bridgepoint Education, Inc Litlang Ltda. (2007). Types of literary criticism. Retrieved from http://www. textetc. com/criticism. html How to cite I’m Going! a Comedy in One Act, Essay examples

Friday, May 1, 2020

Decision Support System

Question: Write an essay on Decision Support System. Answer: Introduction The essay is describing the all features and importance of decision support system. It is the best data management system that is being used to manage the large database now a day. It diminishes the workload of employees as it solves the large number of calculations within a second. Every topic is being discussed in the essay that is important for the implementation of this assignment e.g.- Importance of Decision Support System Mark-Up Type Effects of Mark-Up Suitable Freight Effect of Discount Decision Support System There are different Decision Support Systems in the industry now a day which are very attractive and easy to handle. Every person can interact with the Decision Support System without extreme technical knowledge. It helps in resolving the issues that occur in maintaining the large data and makes the perfect calculations. (TechTarget. 2016) Suitability of Decision Support System It is the most suitable tool for every organization from small to large. It is suitable in the situations where the data is need to be analysed from different tables and need to be summarised at one place by collecting from different sources. It provides the programming solution to that is very easy to learn. (techonthenet.com. 2016) Overall, it is the best tool that can be implemented in every type of organization. Best Mark-up Type The Store and Supplier mark ups are being used in this assignment. Every mark-up has its own conditions. The default mark-up that is being used in this assignment is Store. The exchange rate, freight cost etc. depends upon the mark-up type also, that is why; it should be very good. The chosen type of mark-up depends upon the need of the customer. Mark-up affects the Customers Decision The mark-up affects the customers decision to a great extent and it should be clearly chosen so that it may fulfil the needs of the customers. It affects the profit, price and product sale. That is why; it directs impacts the decision of customers. Effect of Discount on Business Profit The business profit is the main factor in all businesses. It is not the single term it is the term that is affected by so many terms like freight cost, mark-up type, offered discounts etc. The business owner generally gives discount upon the items which are not being sold since a long time and in that case it increases the business profit. If the discount is given on the new arrivals, then it is not good for the business point of view. Recommended Freight Type The freight is the main factor that affects the business to a great extend and this is the reason that it should be chosen very wisely. It affects the cost price of products and that is why affects the sale price and customer decisions. The Johannes Kepler Freight is the default chosen freight in the assignment but it can be changes according to the distance of the customer. Effect of Freight Type It affects the cost price of products and that is why affects the sale price and customer decisions also. The customer always choose the best products from the quality and cost wise and that is why; it is the main factor that throws the great impact on the business. Best Import Country The business should always be done by taking one factor that is profit and reputation. That is why; the best country should be chosen to import the data. The country that takes fewer charges and is the nearest country and the most important thing is that the country has good reputation, should be chosen for import. The Luxembourg country is the best choice at this time. Important Issues for the Import Country Following things are advisable to think about the import country Product Cost Freight Charges Reputation Conclusion The Decision Support System is the best tool that helps in taking the wise decision in the critical circumstances. It helps to the top level management in analysing the large data without any delay and minimizes the workload of the employees also. It works best in the situations where large data handling is the most critical task and a small error may be the reason of huge loss. References [1] techonthenet.com. (2016), Excel Functions, [Online]. Available: https://www.techonthenet.com/excel/formulas/. [Accessed: 28-July-2016] [2] TechTarget. (2016), decision support system (DSS), [Online]. Available: https://searchcio.techtarget.com/definition/decision-support-system. [Accessed: 28-July-2016]

Saturday, March 21, 2020

Free Essays on Tom Sawyer Adventures

The Adventures of Tom Sawyer The Adventures of Tom Sawyer is concerned with the escapades of a young boy living in a Mississippi River town during a summer in the 1840s. Tom lives with his Aunt Polly, his dead mother’s sister, along with his half-brother, Sid, and his cousin, Mary. By the second chapter, Tom’s mischievous character is revealed with the well-known fence whitewashing scene. Tom meets the new girl in town, Becky Thatcher, and falls in love with her. He begins an intense flirtation with her at school, which leads to his asking her to be â€Å"engaged† with him by lunchtime of her first day. Tom’s vagabond friend, Huck Finn, the town drunk’s son, asks Tom to meet him at the cemetery at midnight, to test the wart-curing properties of his dead cat. While there, the boys stumble upon the murder of Dr. Robinson by Injun Joe during a grave-robbing attempt. Muff Potter also part of the gang, is pinned with the crime by Injun Joe. Tom and Huck, however, are the only ones who know the truth. Tom, Huck, and another friend, Joe Harper, decide to run away from St. Petersburg to Jackson’s Island, in the middle of the Mississippi. There they live the life of pirates, frolicking day and night. After several days, the town prepares funeral services for the boys, by the time being convinced of their death. The boys dramatically return to town in the middle of the Sunday church services, and they are forgiven for their mischief. As the murder trial of Muff Potter gets underway, Tom is racked by guilt over allowing a man he knows to be innocent to be convicted. On the final day of the trial, Tom is called as a surprise witness, and he proceeds to finger Injun Joe with the crime, who springs out of the window and escapes. Tom and Huck stumble upon Injun Joe and a stranger at a deserted house on the outskirts of town, and learn of a stash of gold Joe is carrying. Becky Thatcher invited ... Free Essays on Tom Sawyer Adventures Free Essays on Tom Sawyer Adventures The Adventures of Tom Sawyer The Adventures of Tom Sawyer is concerned with the escapades of a young boy living in a Mississippi River town during a summer in the 1840s. Tom lives with his Aunt Polly, his dead mother’s sister, along with his half-brother, Sid, and his cousin, Mary. By the second chapter, Tom’s mischievous character is revealed with the well-known fence whitewashing scene. Tom meets the new girl in town, Becky Thatcher, and falls in love with her. He begins an intense flirtation with her at school, which leads to his asking her to be â€Å"engaged† with him by lunchtime of her first day. Tom’s vagabond friend, Huck Finn, the town drunk’s son, asks Tom to meet him at the cemetery at midnight, to test the wart-curing properties of his dead cat. While there, the boys stumble upon the murder of Dr. Robinson by Injun Joe during a grave-robbing attempt. Muff Potter also part of the gang, is pinned with the crime by Injun Joe. Tom and Huck, however, are the only ones who know the truth. Tom, Huck, and another friend, Joe Harper, decide to run away from St. Petersburg to Jackson’s Island, in the middle of the Mississippi. There they live the life of pirates, frolicking day and night. After several days, the town prepares funeral services for the boys, by the time being convinced of their death. The boys dramatically return to town in the middle of the Sunday church services, and they are forgiven for their mischief. As the murder trial of Muff Potter gets underway, Tom is racked by guilt over allowing a man he knows to be innocent to be convicted. On the final day of the trial, Tom is called as a surprise witness, and he proceeds to finger Injun Joe with the crime, who springs out of the window and escapes. Tom and Huck stumble upon Injun Joe and a stranger at a deserted house on the outskirts of town, and learn of a stash of gold Joe is carrying. Becky Thatcher invited ...

Thursday, March 5, 2020

Definition and Examples of Plain English

Definition and Examples of Plain English Plain English is  clear and direct speech or writing in English. Also called plain language. The opposite of plain English goes by various names: bureaucratese, doublespeak, gibberish, gobbledygook, skotison. In the U.S., the Plain Writing Act of 2010 took effect in October 2011 (see below). According to the governments Plain Language Action and Information Network, the law requires federal agencies to write all new publications, forms, and publicly distributed documents in a â€Å"clear, concise, well-organized† manner that follows the best practices of plain language writing. Based in England, the Plain English Campaign is a professional editing company and pressure group committed to eliminating gobbledygook, jargon and misleading public information. Examples and Observations Plain English, it turns out, is the product of craft: an understanding of the readers needs, the translation of alienating jargon, establishing an easy pace that readers can follow. Clarity of expression comes most of all from a clear understanding of the topic or theme you are writing about. No writer can clarify for the reader what is not clear to the writer in the first place.(Roy Peter Clark, Help! for Writers: 210 Solutions to the Problems Every Writer Faces. Little, Brown and Company, 2011) Plain English (or plain language, as its often called) refers to: The writing and setting out of essential information in a way that gives a cooperative, motivated person a good chance of understanding it at first reading, and in the same sense that the writer meant it to be understood. This means pitching the language at a level that suits the readers and using good structure and layout to help them navigate. It doesnt mean always using simple words at the expense of the most accurate or writing whole documents in kindergarten language . . ..Plain English embraces honesty as well as clarity. Essential information should not lie or tell half-truths, especially as its providers are often socially or financially dominant.(Martin Cutts, Oxford Guide to Plain English, 3rd ed. Oxford University Press, 2009) Plain Writing Act (2011) The federal government is rolling out a new official language of sorts: plain English. . . .[President Barack] Obama signed the Plain Writing Act last fall after decades of effort by a cadre of passionate grammarians in the civil service to jettison the jargon. . . .It takes full effect in October, when federal agencies must start writing plainly in all new or substantially revised documents produced for the public. The government will still be allowed to write nonsensically to itself. . . .By July, each agency must have a senior official overseeing plain writing, a section of its website devoted to the effort and employee training under way. . . .It is important to emphasize that agencies should communicate with the public in a way that is clear, simple, meaningful and jargon-free, says Cass Sunstein, a White House information and regulation administrator who gave guidance to federal agencies in April on how to put the law into place.(Calvin Woodward [Associated Press], Feds Must St op Writing Gibberish Under New Law. CBS News, May 20, 2011) Plain Writing As for plain English writing,  think of it as having three parts: - Style. By style, I mean how to write clear, readable sentences. My advice is simple: write more the way you talk. This may sound simple, but its a powerful metaphor that can revolutionize your writing.- Organization. I suggest starting with your main point almost all the time. That doesnt mean it has to be your first sentence (though it can be)just that it should come early and be easy to find.- Layout. This is the appearance of the page and your words on it. Headings, bullets, and other techniques of white space help your reader seevisuallythe underlying structure of your writing. . . . Plain English is not limited to expressing only simple ideas: it works for all kinds of writingfrom an internal memo to a complicated technical report. It can handle any level of complexity. (Edward P. Bailey, Plain English at Work: A Guide to Writing and Speaking. Oxford University Press, 1996) Criticism of Plain English As well as the arguments in favour (e.g. Kimble, 1994/5), Plain English also has its critics. Robyn Penman argues that we need to consider the context when we write and we cannot rely on a universal principle of plain or simple English. There is some evidence that Plain English revisions do not always work: Penman quotes research including an Australian study which compared versions of a tax form and found that the revised version was virtually as demanding for the taxpayer as the old form (1993), p. 128).We agree with Penmans main pointthat we need to design appropriate documentsbut we still think that all business writers should consider the recommendations coming from Plain English sources. Unless you have clear contrary evidence, they are the safest bet, especially if you have a general or mixed audience. (Peter Hartley and Clive G. Bruckmann, Business Communication. Routledge, 2002)

Monday, February 17, 2020

Airline Business Case Study Example | Topics and Well Written Essays - 500 words

Airline Business - Case Study Example The major drivers which facilitated this trend are: the deregulation of the European air travel sector; the establishment of the European Union; the 9/11 tragedy; the rapid technological advancement; and change in customers' lifestyle and preferences. It is irrefutable that the deregulation of the European airline industry primarily contributed to the rise of low cost carriers. It can be recalled that deregulation has lowered the barrier to entry in the industry as well as enhanced the competitiveness of the players which are previously receiving subsidy from the government. This, in turn, largely contributes to the cost efficiency of airline operators allowing them to charge lower prices to passengers. While this is true for budget airline like EasyJet large carriers have suffered significantly from the deregulation as this opens the door for the entry of smaller firms and heightening the competition among industry players. The establishment of the European Union affects the airline industry has the same effect like the deregulation of the sector. This has opened up markets and lowered operating costs, encouraging the proliferation of low cost carriers (Sorensen 2006). The 9/11 tragedy which left terror worldwide has also helped in lowering the cost of air tra

Monday, February 3, 2020

MICROECONOMICS Essay Example | Topics and Well Written Essays - 1250 words

MICROECONOMICS - Essay Example Economics, as stated is the study of both individual and the government and business behavior in terms of price, interest rates, jobs, poverty, employment, etc. As such, it has to deal with groups of people which is classified into categories namely households, business and government to facilitate the analysis of behavior. While individual behavior study is termed micro-economics, study of people at large is called macro-economics. Also, actual behavior of people falls under descriptive economics while advice or choices of economists comes under normative economics. It is evident that when policies and structures are to be studied in totality, individual responses can deliver highly variable results. As a result, economists have simplified individual responses by setting out average of a large number of responses and which behave in a similar fashion or towards a common goal. On the basis of this concept, assumptions emerge which turn into simplified models or theories of economics because they demonstrate a common and shared behavior of a large group of people. For instance, assumption of profit maximization relates to suppliers because in a particular situation, average response of a number of suppliers would be that of maximizing their profits. Likewise, assumption of satisfaction maximization applies to buyers as they tend to derive maximum satisfaction from their investments. Market in economics refers to the place where interaction between buyer and seller takes place. Level of scarcity in the production or delivery of a service determines its market value. Surplus product comes at lower price while scarce product is associated with higher price. When government intervention happens in the market due to price or supply concerns, it gets turned to public goods. Scholars of economics are continuously confronted with some difficult terms

Sunday, January 26, 2020

The Biological Effects Of Ionizing Radiation Biology Essay

The Biological Effects Of Ionizing Radiation Biology Essay The biological effects of ionizing radiation are determined by both the radiation dose and the radiation quality ionization density. To understand the radiation protection concerns associated with different types of ionizing radiation, knowledge of both the extent of exposure and consequent macroscopic dose absorbed gray value, as well as the microscopic dose distribution of the radiation modality is required. The definitions of these variables are discussed below but in general to advance the knowledge of the biological effects of different radiation types one needs to know the dose absorbed, the radiation quality and effectiveness of a particular radiation type to induce biological damage. In this study the biological effect of high energy neutrons is compared to that of a reference radiation type 60Co ÃŽÂ ³-rays for a cohort of donors, mostly radiation workers. Comparisons are made at different dose levels in blood cells from each donor to ascertain the relative biological effectiveness of the test radiation modality against that of a recognized reference radiation (Hall, 2005). Such studies are essential to determine the radiation quality for high energy neutron sources applicable to practises in radiation protection. In some nuclear medicine applications radionuclides are used to treat malignant disease. For this the use of short lived alpha particle emitters or other radiation modalities that deliver high ionization densities in cells, are particularly attractive. This as the cellular response in relation to inherent radiosensitivity of the effected cells is thought to be more consistent compared to the use of radionuclides that emit radiation with a lower ionization density e.g. ÃŽÂ ²-particles. The relative biological effectiveness of the high energy neutrons used in this study is followed as a function of the inherent radiosensitivity of different individuals. This allows the identification of cell populations that are relatively sensitive or relatively resistant to radiation. As such research material is available to investigate cellular response too Auger electrons. The latter is known to induce biological damage akin to that of alpha particles. A short description of the physical and biological variables applicable to this study is summarised below. Ionizing Radiation The term ionizing radiation refers to both charged particles (e.g., electrons or protons) and uncharged particles (e.g., photons or neutrons) that can impart enough energy to atoms and molecules to cause ionizations in that medium, or to initiate nuclear or elementary-particle transformations that in turn result in ionization or the production of ionizing radiation. Ionization produced by particles is the process by which one or more electrons are liberated in collisions of the particles with atoms or molecules (The International Commission on Radiation Units and Measurements [ICRU] Report 85, 2011). Interaction of Ionizing Radiation with Matter Ionizing radiation is not restricted to ionization events alone. Several physical and chemical effects in matter such as: heat generation, atomic displacements, excitation of atoms and molecules, destruction of chemical bonds and nuclear reactions may occur. The effects of ionizing radiation on matter depend on the type and energy of radiation, the target, and the irradiation conditions. Radiation can be categorized in terms of how it induces ionizations: Directly ionizing radiation, consist of charged particles such as electrons, protons and alpha particles. Indirectly ionizing radiation consists of neutral particles and/or electromagnetic radiation such as neutrons and photons (ÃŽÂ ³-rays and X-rays). Ionising radiation interacts with matter by: Interaction with the electron cloud of the atom, or by Interaction with the nucleus of the atom. Types of ionizing radiation linked to this study ÃŽÂ ³-rays Ionizing photons (ÃŽÂ ³- and X-rays) are indirectly ionising radiation. These wave like particles have zero rest mass and carry no electrical charge. Low energy (E>2m0c2) may be absorbed by atomic nuclei and initiate nuclear reactions (Cember, 1969). The charged electrons emitted from the atoms, produce the excitation and ionisation events in the absorbing medium. Neutrons Neutrons, similar to ionizing photons are indirectly ionizing radiations; however, these particles do have a rest mass. There is negligible interaction between neutrons and the electron cloud of atoms since neutrons do not have a net electrical charge (Henry, 1969). The principle interactions occur through direct collisions with atomic nuclei during elastic scattering events. In this process, ionisation is produced by charged particles such as recoil nuclei and nuclear reaction products. The production of secondary ionising photons will result in the release of energetic electrons. In turn these charged particles can deposit energy at a considerable distance from the interaction sites (Pizzarello, 1982). Auger electrons Auger electron emission is an atomic-, not a nuclear process. In this process an electron is ejected from an orbital shell of the atom. A preceding event, e.g. electron capture (EC) or internal conversion (IC) leaves the atom with a vacant state in its electron configuration. An electron from a higher energy shell will drop into the vacant state and the energy difference will be emitted as a characteristic x-ray (Cember, 1969). The energy of the x-ray (Ex-ray) being the difference in energy (E) between the two electron shells L and K. Ex-ray = EL -EK Alternatively, the energy may be transferred to an electron of an outer shell, causing it to be ejected from the atom (Fig. 1). The emitted electron is known as an Auger electron and similarly to the x-ray has an energy: EAuger = EΆ -EB where: EΆ = the energy of inner-shell vacancy energy of outer-shell vacancy EB = binding energy of emitted (Auger) electron Auger emission is favoured for, low-Z materials where electron binding energies are small. Auger electrons have low kinetic energies; hence travel only a very short range in the absorbing medium (Cember, 1969). File:Auger Process.svg Fig. 1: Schematic representation of the Auger electron emission process, where an orbital electron is ejected following an ionization event. Dosimetric Quantities Several dosimetric quantities have been defined to quantify energy deposition in a medium when ionizing radiation passes through it. Radiation fields are well described by physical quantities such as particle fluence or air kerma free in air are used. However these quantities do not relate to the effects of exposure on biological systems (International Commission on Radiological Protection [ICRP] Publication 103, 2007). The absorbed dose, D, is the basic physical quantity used in radiobiology, radiology and radiation protection that quantifies energy deposition by any type of radiation in any absorbing material. The International System of Units (SI) of absorbed dose is joule per kilogram (J.kg-1) and is termed the gray (Gy). Absorbed dose, D, is defined as the quotient of mean energy, dÃŽÂ µ, imparted by ionising radiation in a volume element and the mass, dm, of the matter in that volume (Cember, 1969). The absorbed dose quantifies the energy imparted per unit mass absorbing medium, but does not relate this value to radiation damage induced in cells or tissue. The radiation weighted dose (HT) is used as a measure of the biological effect for a specific radiation quality on cells or tissue. It is calculated from equation where DT,R is the mean absorbed dose in a tissue T due to radiation of type R and wR is the corresponding dimensionless radiation weighting factor. The unit of radiation weighted dose is J.kg-1 and is termed the sievert (Sv). Radiation weighting factors are recommended by the International Commission on Radiological Protection (International Commission on Radiological Protection [ICRP] Publication 103, 2007) and are derived from studies on the effect of the micro-deposition of radiation energy in tissue and on its carcinogenic potential. Linear Energy Transfer (LET) Ionizing radiation deposits energy in the form of ionizations along the track of the ionizing particle. The spatial distribution of these ionization events is related to the radiation type. The term linear energy transfer (LET) relates to the rate at which secondary charged particles deposit energy in the absorbing medium per unit distance (keV/ µm). LET is a realistic measure of radiation quality (Duncan, 1977). The LET (L) of charged particles in a medium is defined as the quotient of dE/dl where dE is the average energy locally imparted to the medium by a charged particle of specified energy in traversing a distance dl (Pizzarello, 1982). For high energy photons (x- and ÃŽÂ ³-rays), fast electrons are ejected when energetic photons interact with the absorbing medium. The primary ionization events along the track of the ionizing particle are well separated. This type of sparsely ionizing radiation is termed low-LET radiation. The LET of a 60Cobalt teletherapy source (1.3325 and 1.1732 MeV) is in the range of 0.24 keV/ µm (Vral et al., 1994). Neutrons cause the emission of recoil protons, alpha particles and heavy nuclear fragments during scattering events. These emitted charged particles interact more readily with the absorbing medium and cause densely spaced ionizing events along its track. The p66(Be) neutron beam used in this study has an ionization density of 20 keV/ µm and hence regarded as high-LET radiation. Auger electrons travel very short distances in the absorbing medium due to their low kinetic energies. All the energy of these particles is liberated in small volumes over short track lengths. Ionization densities are therefore very high, up to 40 keV/ µm this is comparable to high-LET alpha particles (Godu et al., 1994). Relative Biological Effectiveness (RBE) The degree of damage caused by ionizing radiation depends firstly on the absorbed dose and secondly on the ionization density or quality of radiation. Variances in the biological effects of different radiation qualities can be described in terms of the relative biological effectiveness (RBE). RBE defines the magnitude of biological response for a certain radiation quality compared to a distinct reference radiation. It is expressed in terms of the ratio (Quoc, 2009): Megavoltage X-rays or 60Co ÃŽÂ ³-rays are commonly employed as the reference radiation since these are standard therapeutic sources of radiation. Thus for an identical dose neutrons the biological effect observed would be greater, compared to 60Co ÃŽÂ ³-rays. The fundamental difference between these radiation modalities is in the spatial orientation or micro deposition of energy. Furthermore, RBE varies as a function of the dose applied increase in RBE is noted for a decrease in dose. By evaluating dose response curves (Fig 2), it is evident that the shoulder of the neutron curve is much shallower (smaller ÃŽÂ ²-value) compared to the reference radiation curve. Therefore changes in RBE are prominent over low dose ranges (Hall, 2005). Fig 2: Dose response curves based on the linear quadratic model demonstrate differences in RBE as a function of dose. Through evaluation of the biological effect curves it is apparent that the RBE for a specific radiation quality may vary. This is characterized by the type of tissue or cells being investigated, dose and dose rates applied oxygenation status of the tissue, energy of radiation and the phase of the cell cycle and inherent radiosensitivity of cells. The RBE increases with a decrease in dose, to reach a maximum RBE denoted RBEM this is calculated from the ratio of the initial slope of the dose response curves for both radiation modalities. RBE LET relationship For a given absorbed dose, differences in the biological response for several cell lines, exposed to different radiation qualities have been demonstrated (Slabbert et al., 1996). Cells exposed to a specified dose low LET radiation do not exhibit the same biological endpoint than those exposed to same dose high LET radiation. This since with low LET radiation a substantial amount of damage may be repaired because the energy density imparted to each ionization site is relatively low. The predominant mode of interaction for this radiation type is indirect through chemical attack from radiolysis of water. As the LET increases, for a specific dose, fewer sites are damaged but the sites that are located along the track of the ionizing particle are severely damaged because more energy is imparted. Thus the probability of direct interaction between the particle track and the target molecule increases with an increase in LET. The RBE of radiation can be correlated with the estimates of LET values. However, as the LET increases, exceeding 10keV/ µm it is no longer possible to assign a single value for the RBE. Beyond this LET, the shape of the cell survival curve changes markedly in the shoulder region compared to low-LET. Since RBE is a measure of the biological effect produced, comparison of the low-LET and high-LET curves will reveal that RBE increases with decreasing dose (Hall, 2005). The average separation in ionizing events at LET of about 100 keV/ÃŽÂ ¼m is equal to the width of deoxyribonucleic acid (DNA) double strand molecule (Fig. 3). Further increase in LET results in decreased RBE since ionization events occur at smaller intervals than DNA molecule strand separation (Fig. 3) and this energy imparted does not contribute to DNA damage. Fig 3: Average spatial distribution of ionizing events for different LET values in relation to the DNA double helix structure (Hall 2005). Cellular Radiosensitivity Tissue radiosensitivity models In 1906 the radiobiologists Bergonie and Tribondeau established a rule for tissue radiosensitivity. They studied the relative radiosensitivities of cells and from this could predict which type of cells would be more radiosensitive (Hall, 2005). Bergonie and Tribondeau realized that cells were most sensitive to radiation when they are: Rapidly dividing (high mitotic activity). Cells with a long dividing future. Cells of an unspecialised type. The law of Bergonie and Tribondeau was later adapted by Ancel and Vitemberger; they concluded that radiation damage is dependent on two factors: the biological stress on the cell. the conditions to which the cell is exposed pre and post irradiation. Cell division causes biological stress thus cells with a short doubling time express radiation damage at an earlier stage than slowly dividing cells. Undifferentiated rapidly dividing cells therefore are most radiosensitive (Hall, 2005). A comprehensive system of classification was proposed by Rubin and Casarett, cell populations were grouped into 4 categories based on the reproduction kinetics: Vegetative intermitotic cells were defined as rapidly dividing undifferentiated cells. These cells usually have a short life cycle. For example: erythroblasts and intestinal crypt cells and are very radiosensitive. Differentiating intermitotic cells are characterized as actively dividing cells with some level of differentiation. Examples include: meylocytes and midlevel cells in maturing cell lines these cells are radiosensitive. Reverting postmitotic cells are regarded as to not divide regularly and generally long lived. Liver cells is an example of this cell type, these cell types exhibit a degree radioresistance. Fixed postmitotic cells do not divide. Cells beloning to this classification are regarded to be highly differentiated and highly specialized in both morphology and function. These cells are replaced by differentiating cells in the cell maturation lines and are regarded as the most radioresistant cell types. Nerve and muscle cells are prime examples (Hall, 2005). Michalowski proposed a type of classification which divides tissues into hierarchical (H-type) and flexible (F-type) populations. Within this classification cells are grouped in 3 distinct categories: Stem cells, that continuously divide and reproduce to give rise to both new stem cells and cells that eventually give rise to mature functional cells. Maturing cells arising from stem cells and through progressive division eventually differentiate into an end-stage mature functional cell. Mature adult functional cells that do not divide Examples of H-type populations include the bone marrow, intestinal epithelium and epidermis; these cells are capable of unlimited proliferation. In F-type populations the adult cells can under certain circumstance be induced to undergo division and reproduce another adult cell. Examples include; liver parenchymal cells and thyroid cells. The two types represent the extremes in cell populations. It should be noted that most tissue populations exist between the extremes, these exhibit characteristics of both types where mature cells are able to divide a limited number of times. The sensitivity to radiation can be attributed to the length of the life cycle and the reproductive potential of the critical cell line within that tissue (Hall, 2005). Cell cycle dependent radiosensitivity As cells progress through the cell cycle various physical and biochemical changes occur (Fig. 4). These changes influence the response of cells to ionizing radiation. Variations in radiosensitivity for several cell types at different stages of the cell cycle has been documented (Hall, 2005). Following the law of Bergonie and Tribondeau that cells with high mitotic activity are most radiosensitive, it was found that cells in the mitotic phase (M-phase) of the cell cycle are most sensitive. Late stage gap 2 (G2) phase cells are also very sensitive with gap 1 (G1) phase being more radioresistant and synthesis (S phase) cells the most resistant (Domon, 1980). Fig. 4: Cell cycle of proliferating cells representing the different phases leading up to cell division. The G0 resting phase for cells that do not actively proliferate has been included since T-lymphocytes naturally occur in this phase (Hall, 2005). Nonproliferating cells, generally cells that are fully differentiated, may enter the rest phase G0 from G1 and remain inactive for long periods of time. Peripheral T-lymphocytes seldom replicate naturally and remain in G0 indefinately. Lymphocyte Radiosensitivity The hematopoietic system is very sensitive to radiation. Differential blood analyses are routinely employed as a measure of radiation exposure. This measurement is based on the sensitivity of stem cells and the changes observed in the constituents of peripheral blood due to variations in transit time from stem cell to functioning cell (Hall, 2005). It has been shown that lymphocytes, although they are resting cells (G0 phase) which do not actively proliferate nor do have a long dividing future hence do not meet the criteria of a radiosensitive cell type as described above are of the most radio sensitive cells. The reasons for their acute sensitivity cannot be explained (Hall, 2005). Furthermore two distinct subpopulations T-lymphocytes with respect to radiosensitivity were found in peripheral blood. The small T-lymphocyte which is extremely radiosensitive and disappears almost completely from the peripheral blood at doses of 500 mGy (Kataoka, 1974, Knox, 1982 and Hall, 2005). Cytogenetic expression of ionizing radiation induced damage The primary target in radiotherapy is the double helix deoxyribonucleic acid (DNA) molecule (Rothkam et al. 2009). This macro molecule contains the genetic code critical to the development and functioning of most living organisms. The DNA molecule consists of two strands held together by hydrogen bonds between the bases. Each strand is made up of four types of nucleotides. A nucleotide consists of a five-carbon sugar (deoxyribose), a phosphate group and a nitrogen containing base. The nitrogen containing bases are adenine, guanine, thymine or cytosine. Base pairing between two nucleotide strands is universally constant with adenine pairing with thymine and guanine with cytosine (Fig. 5). This attribute permits effective single strand break repair since the opposite strand is used as a template during the repair process. The base sequence within a nucleotide strand differs; the arrangement of bases defines the genetic code. The double helix DNA molecule is wound up on histones and bou nd together by proteins to form nucleosomes. This structure is folded and coiled repeatedly to become a chromosome. Fig. 5: The double helix structure of a DNA molecule consists of two neucleotide strands held together by hydrogen bonds between the bases. Figure modified from http://evolution.berkeley.edu/evolibrary/article/history_22 by P Beukes. Ionizing radiation can either interact directly or indirectly with the DNA strand. When an ionization event occurs in close proximity to the DNA molecule direct ionization can denature the strand. Ionization events that occur within the medium surrounding the DNA produce free radicals such as hydrogen peroxide through radiolysis of water. Damage induced by ionizing radiation to the DNA include base damage (BD), single strand breaks (SSB), abasic sites (AS), DNA-protein cross-links (DPC), and double strand breaks (DSB) (Fig. 6). Fig. 6: Examples of several radiation induced DNA lesions. Figure modified from Best B (9) by P Beukes. Low-LET radiation primarily causes numerous single strand breaks, through direct and indirect interaction (Hall, 2005). Single strand breaks are of lesser biological importance since these are readily repaired by using the opposite strand as a template. High-LET radiation damage is dominated by direct interactions with the DNA molecule. Densely ionizing radiation has a greater probability to induce irreparable or lethal double strand breaks since energy deposition occurs in discrete tracks (Hall, 2005). The number of tracks will be fewer but more densely packed compared to low-LET radiation of equivalent doses. Several techniques to quantify chromosomal damage and chromatid breaks have been established. These range from isolating DNA and passing it through a porous substrate or gel (Hall, 2005) by applying an external potential difference too advanced techniques of visually observing and numerating chromosomal aberrations of interphase cells. Cytogenetic chromosome aberration assays of peripheral blood T-lymphocytes to assess radiation damage include but are not limited to: premature chromosome condensation (PCC) assay, metaphase spread dicentric and ring chromosome aberration assay (DCA), metaphase spread fluorescence in situ hybridisation (FISH) translocation assay and cytokinesis blocked micronuclei (CBMN) assay (Fig. 7). Fig. 7: Different cytogenetic assays on peripheral T-lymphocytes for use in biological dosimetry. Figure modified from Cytogenetic Dosimetry IAEA, 2011. PCC occurs when an interphase cell is fused with a mitotic cell. The fusion causes the interphase cell to produce condensed chromosomes prematurely. Chromosomal aberrations can thus be analysed immediately following irradiation without the need for mitogen stimulation or cell culturing. Numeration of dicentrics in metaphase spreads has been used with great success to assess radiation damage in cells since the 1960s (Vral et al, 2010). The incidence of these aberrations follows a linear quadratic function with respect to the dose. Unstable aberrations like dicentrics or centric rings are lethal to the cell hence not passed on to daughter cells (Hall, 2005). In contrast translocations are stable aberrations; these are not lethal to the cell and passed on to daughter cells. Examination of translocations thus provides a long term history of exposure. Although the abovementioned techniques are very accurate and well described, the complexity and time consuming nature of the assays has stimulated the development of automated methods of measuring chromosomal damage. Micronuclei (MN) formation in peripheral blood T-lymphocytes lends itself to automation, since the outcome of radiation insult is visually not too complex with limited variables. DNA damage incurred from ionizing radiation or chemical clastogens induce the formation of acentric chromosome fragments and to a small extent malsegregation of whole chromosomes. Acentric chromosome fragments and whole chromosomes that are unable to engage with the mitotic spindle lag behind at anaphase (Cytogenetic Dosimetry IAEA, 2011). Micronuclei originate from these acentric chromosome fragments or whole chromosomes which are excluded from the main nuclei during the metaphase/anaphase transition of mitosis. The lagging chromosome fragment or whole chromosome forms a small separate nucleus visible in the cytoplasm of the cell. Image recognition software can thus be employed to quantify radiation damage by applying classifiers that describe cell size, staining intensity, cell separation, aspect ratio and cell characteristics when numerating MN frequency in BN cells. The classifiers are fully customizable depending on cell size, staining technique or cell type that will be used. Rationale for this study The principal objective of this study is to define RBE variations for high-LET radiation with respect to radiosensitivity. Specifically this is done for very high energy neutrons and Auger electrons. In general the response of different cell types vary much more to treatment with low-LET radiation compared to high-LET radiation (Broerse et al. 1978). Radiosensitivity differences have been demonstrated for different cancer cell lines (Slabbert et al. 1996) as well as various clonogenic mammalian cells (Hall, 2005) exposed to both high and low-LET radiation. In general there is an expectation and in certain cases some experimental evidence to support less variations in radiosensitivities of cells to high-LET radiation. Furthermore the ranking in the relative radiosensitivity of cell types changed for neutron treatments compared to exposure to X-rays (Broerse et al. 1978). To quantify the radiation risk of individuals exposed to cosmic rays or mixed radiation fields of neutrons and ÃŽÂ ³-rays, several experiments were conducted to ascertain biological damage induced by neutron beams of various energies (Nolte et al., 2007). Clonogenic survival data (Hall, 2005), dicentric chromosome aberrations (Heimers 1994) and micronuclei formation (Slabbert et. al 2010) have been followed. Chromosome aberration frequencies have been quantified and this represent radiation risk to neutron energies ranging from 36 keV up to 14.6 MeV (Schmid et al. 2003). To complement these studies additional measurements have been made for blood cells exposed to 60 MeV and 192 MeV quasi monoenergetic neutron beams (Nolte et al. 2007). Comparisons of RBE values obtained in these studies are shown in figure 1. Significant changes in the maximum relative biological effectiveness (RBEM) of these neutron sources are demonstrated as a function of neutron energy, with a maximum value of 90 at 0.4 MeV. RBEM drop to  ±15 for neutron energies higher than 10 MeV and it appears that the RBEM remain constant up to 200 MeV. The RBEM value of 47 -113 reported by Heimers et al. (1999) is not consistent with these observations. Fig. 1: RBEM values for neutrons of different energies after Nolte et al. (2007) The data shown in Fig. 1 was obtained by using the blood of a single donor. This to ensure consistency in the biological response for different neutron energies used in different radiation facilities in different parts of the world. Keeping the donor constant has the advantage that only a single data set for the reference radiation was needed. These measurements were done over several years. In all these studies, dicentric chromosome aberrations were followed. As informative as these investigations may be, it is doubtful if RBE values obtained from blood samples from a single donor are indeed representative for the wider population to state radiation weighting factors. It is unclear if RBE values for high energy neutrons will vary when measured with cells with different inherent radiosensitivities. Warenius et al. (1994) demonstrated that the RBE of a 62.5 MeV neutron beam increases with increase in radioresistance to 6 MV X-rays. Similarly Slabbert et al (1996) using a 29 MeV p(66)/Be neutron with an average energy of 29 MeV, noted a statistically significant increase in the RBE values for cell types with increased radioresistance to 60Co ÃŽÂ ³-rays. Although these investigators used 11 different cell types, few of these were indeed radioresistant to 60Co ÃŽÂ ³-rays. Close inspection of the data shows that the relationship between neutron RBE and radioresistance to photons disappear when the cell type with the highest resistance to ÃŽÂ ³-rays (Gurney melanoma) is removed from the data set Slabbert et al. 1996). In a follow up study the authors failed to demonstrate the relationship for a p(66)/Be neutron beam but such a relationship was demonstrated for a d14/Be neutron beam (Slabbert et al. 2000). It therefore appears that the relationship for RBE and radioresistance is dependent on the selection of cells used in the study as well as the neutron energy. Using lymphocytes Vral et al. (1994) demonstrated a clear reduction RBEM values for 5,5 MeV neutrons with an increase in the ÃŽÂ ±-values of dose effect curves obtained for 60Co ÃŽÂ ³-rays. This for lymphocytes obtained from six healthy donors. Using only four donors Slabbert et al. (2010) also demonstrated a relationship between RBEM neutrons and radiosensitivity to 60Co y rays. In the latter case the RBEM values are lower as can be expected since these investigators used a higher energy neutron source. Although a significant relationship between these parameters has been demonstrated by the investigators, the cohort of 4 donors in the study is very small. In fact 2 out of the 4 donors have different RBEM values but appear to have the same radiosensitivity. A study using larger number of donors with blood cells exposed to high energy neutrons is clearly needed. This in particular too verify the findings above indicating a different wR for donors of different sensitivity. The studies of RBE variations with neutron energy by Schmid et al., (2003), Nolte et al. (2005) and were conducted dicentric formations observed in metaphase spreads. It is known that more than six months were used to analyse the data for different doses for blood cells obtained from a single donor exposed to a single neutron energy. It follows that some method of automation to assist the radiobiological evaluation of cellular radiation damage is needed to quantify wR values as a function of radiosensitivity. Recently a semi-automated image analysis system, Metafer 4, this holds promise to test numerous donors for micronuclei formations Study to include more participants hence Metaferà ¢Ã¢â€š ¬Ã‚ ¦.

Saturday, January 18, 2020

Conflict with “Macbeth” and “World War Poetry” Essay

During this essay I am going to write about the many diverse ways in which conflict is presented in William Shakespeare’s Macbeth and Wilfred Owen’s Poetry of World War 1. I will be comparing the ways in which Macbeth and 3 poems written by Owen; Mental Cases, The Next War and Dulce Et Decorum Est, link with each other. Macbeth is a play written in 1606 by Shakespeare who wrote plays to entertain his audience. On the other hand, Owen was a soldier in World War 1 when he wrote famous poems; he wrote them to tell us about the tragedies of war and he expressed his thoughts and feelings about war and conflict. Owen’s poems are influenced by his own experiences of war. In Macbeth the conflict shown by Macbeth and the other characters, gives us an idea of how Macbeth’s rivalry between certain characters in the play depicted the whole play itself. For example, Macbeth’s conflict with King Duncan shows how Macbeth was such an easy target for the witches bec ause they predicted he would be the next Thane of Cawdor which came true, then they predicted he would be the next King, but when Duncan announced Malcolm to be the next heir to the throne, Macbeth become insecure and had the thoughts of killing Duncan. â€Å"I have no spur to prick the sides of my intent, but only vaulting ambition which o’erleaps itself† – Macbeth’s excessive ambition is like a horse that tries to jump too high but it falls on the other side of the fence, also Shakespeare uses a metaphor to describe Macbeth’s ambition as ‘vaulting’ like a horse. Shakespeare brings the idea of Macbeth killing Duncan to life. Similarly, Wilfred Owen presents the conflict in his poems in ways which he relentlessly unveils the full scale of the war’s horrors. For example, in Owen’s poem ‘Mental Cases’, the conflict the soldiers have with the violent conditions they had to live in, Owen presents the mental torment suffered by the patients in this poem. He uses the simile â€Å"like a wound† to show that their wounds are still fresh and present in their minds. The words such as ‘blade’ and ‘bleeds afresh’ suggest that they have be en brutally ripped open by the conflict happening in their minds. Owen’s poem ‘Mental Cases’ shows us the mental anguish the soldiers had to go through during the World War. He uses the simile â€Å"baring teeth that leak like skulls, teeth wicked† to describe the soldiers as skeletons because they’re half dead from fighting continuously in the war; this shows how the poems title ‘Mental Cases’ links with the whole concept of the soldiers being half dead because their minds have been taken over by  the trauma of the war. â€Å"Batter of guns and shatter of flying muscles† – the use of violent imagery to emphasise the way in which the soldiers are continuously surrounded by gun-shots (‘batter of guns’) and dead bodies (‘flying muscles’). â€Å"Dawn breaks open like a wound that bleeds afresh† – Owen uses a simile, also a personified phrase to highlight the way the soldiers wake up to constant violence around them. Wilfred Owen uses words such as ‘skulls’ to show that the soldiers were like skeletons; half dead. Also he uses ‘ravished’ to give more power to the poem, to demonstrate that the horrors have taken over the soldiers’ minds. This poem links with Macbeth due to the way in which Macbeth is mentally tormented because of the crimes he’s committed which are now acting upon him, just the way the patients are mentally tormented because of the tragic war. Shakespeare uses the personified phrase â€Å"art th ou not fatal vision sensible to feeling as to sight?† to accentuate that Macbeth can only see the dagger in his mind but it’s not really there. â€Å"Here’s the smell of blood still, all the perfumes of Arabia will not sweeten† – Shakespeare manipulates the use of the senses to show that Lady Macbeth is saying that there is no perfume of this world which shall ‘sweeten’ our sinful hands; which emphasises that Lady Macbeth still thinks about the murder of King Duncan. Shakespeare also uses the simile â€Å"that not look like inhabitants o’the earth† to show that the witches aren’t humans; they don’t belong to the earth. â€Å"If it were done when ‘tis done, then ‘twere well it were done quickly† Shakespeare presents the idea of past and present; to kill Duncan quickly would be better. â€Å"Thy bones are marrowless, thy blood is cold† – Macbeth says to the ghost of Banquo; he has no marrow in his bones, his blood is cold. Shakespeare uses words such as ‘fatal’ to show the mental torment Macbeth is going through whilst h e sees the dagger in his mind. Also he uses ‘inhabitants’ to describe the way the witches look; they don’t look like they live on earth. In Owen’s poem ‘The Next War’ he presents the inner conflict of the war because the poem is based on the idea of not being afraid of death but getting used to the fact that death comes everyday to them. In the beginning of the poem Owen has written a quote from Siegfried Sassoon â€Å"war’s a joke for me and you, while we know such dreams are true† – this is an unusual sonnet because sonnets are usually on love and romance, but this one is on war. Owen uses personification like â€Å"out there we’ve walked quite friendly up to Death; sat  down and eaten with him, cool and bland† to emphasise that mostly all the soldiers are used to seeing people die and when death comes its normal for them. Also Owen describes death as ‘cool’ and ‘bland’ – these are oxymorons because they have an unusual perspective of war. â€Å"He’s spat at us with bullets and he’s coughed† – Owen u ses personification to show how death has tortured the soldiers. Owen uses many language techniques to bring the idea of welcoming death to the soldiers’ lives. Wilfred Owen uses words like ‘courage’ to emphasise the soldiers’ characters. Also he uses ‘green thick odour’ to represent the ‘odour’ as the poisonous gas that caused many soldiers’ deaths. This poem links with Macbeth because in this poem Owen talks about the courage these soldiers had and how they got used to seeing their men die all the time, however, in Macbeth, Macbeth is looked at as ‘brave Macbeth’ who has ‘disdaining fortune’ because he won the battle for Scotland and was looked at as a hero. â€Å"For brave Macbeth – well he deserves that name – disdaining fortune, with his brandish’d steel† – Shakespeare describes Macbeth as a courageous warrior. However, during the play we find out that Macbeth has planned to kill Duncan, but then feels a slight regret in going fourth with the murder â€Å"we will proceed no further in this business. He hath honour’d me of late, and I have bought golden opinions from all sorts of people†. In this scene, Lady Macbeth attacks Macbeths manliness and makes him feel like he less of a man â€Å"And live a coward in thine own esteem†. â€Å"But screw your courage to the sticking place† – Shakespeare uses a metaphor here to show the power in which Lady Macbeth has; she wants Macbeth to tighten his courage to the limit, so he can go fourth and kill Duncan. Lady Macbeth tries to convince him by calling him a ‘coward’ and unmanly. Macbeth is convinced enough to murder Duncan which eventually lead to his own down fall. ‘Dulce Et Decroum Est’ meaning ‘Die for Your Country’ is another famous poem of Wilfred Owen’s where it links to battlefield conflict and inner conflict. The poem is based on the whole concept of war, and how the soldiers fight for their country throughout the world war. â€Å"Bent double like old beggars, coughing like hags† – Owen uses two similes to describe the soldiers as ‘beggars’ and ‘hags’, due to the way they live in. â€Å"Men marched asleep† – this use of characterisation brings to life the way in which the soldiers were continuously marching during their days, and nights. Owen also uses an oxymoron to bring sarcasm into the poem  Ã¢â‚¬Å"of gas shells dropping softly behind† – gas shells are usually very loud and dangerous but Owen makes out the gas shells were ‘soft’. â€Å"As under a green sea I saw him drowning.† – a metaphor to describe the poisonous gas, and Owen’s persona of his friend drowning in the gas. â€Å"Guttering, choking, and drowning† – the use of onomatopoeia gives effect of the way in which Owen presents the conflict of the war. Owen also uses personified techniques to show the inner conflict of how the soldiers’ minds were taken over by the tragic war â€Å"If you could hear, at every jolt, the blood† – the effect that Owen uses to ‘hear the blood’. Owen gives the impression that these soldiers are broken and describes them to be helpless. Wilfred Owen uses words such as ‘deaf’ from the gun shots and bombs and ‘blind’ from the tear gas and smoke; he uses pitiful language to reveal the reality of war. This poem links with Macbeth, because Owen talks about the way in which the soldiers die for their country and linking back to Macbeth, he fought a battle for his country. However, the soldiers in the poem are described as ‘beggars’ and ‘hags’, on the other hand, Macbeth is described as ‘brave’. Macbeth has a higher reputation because he had killed the enemy of King Duncan’s. Shakespeare describes the nature of war as if it is a game or a sport â€Å"doubtful it stood, as two spent swimmers that do cling together† – using the word ‘swimmer’ relates to sport and ‘doubtful’ makes them want to try harder and think of swimming where they are pushing the water away racing to the finish line makes the reader create a picture of Macbeth and Banquo slashing away with their swords creating a sea of dead soldiers and blood behind them fighting their way to glory. It is only at the end of the play that Macbeth finally discovers his fate; after being told that Macduff had been, â€Å"untimely ripped from his mothers’ womb†. Macbeth describes the witches as â€Å"Juggling Fiends† Macbeth is accusing the witches of deliberately juggling their words so that he could not understand them. This is a clever quote as Macbeth has just realised his life is in ruins, but the audience knew this earlier. The witches have changed Macbeth from a brave warrior to an evil, murderous, traitor, underlining the conflict of good and evil. â€Å"By the pricking of my thumbs, something wicked this way comes† – this quote is significant as it illustrates the change in Macbeth throughout the play, now even the witches consider Macbeth to be evil. However, when looking at the path of destruction that Macbeth has left behind him it isn’t very  surprising. Just one man driven by his ambition to be king has led to a chain reactio n of murders. There are many important conflicts in Macbeth, like the conflict between Lady Macbeth and Macbeth, the conflict between the good which is represented by Macduff and the evil which is represented by Macbeth, and Macbeth versus himself, his inner struggle, and all of those conflicts lead to Macbeth’s down fall. Shakespeare gave a truthful, but interesting effect to show war and conflict in that time and age of Shakespeare. There are also many significant conflicts in the World War 1 which Wilfred Owen wrote about in all of his famous poems, like the conflict between the soldiers and death; the way in which the soldiers have to welcome death because it’s likely they will die. This conflict leads to the soldiers becoming mentally tormented. Owen always revealed the truth about war and conflict.